Phospho-Dab1 (Tyr220) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-Dab1 (Tyr220) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-Dab1 (Tyr220) antibody detects endogenous levels of Dab1. Function: Adapter molecule functioning in neural development. May regulate SIAH1 activity.Subunit Structure: Associates with the SH2 domains of SRC, FYN and ABL (By similarity). Interacts (phosphorylated on tyrosine residues) with CRK and CRKL (via respective SH2 domain) (By similarity). Interacts with SIAH1, LRP8 and VLDLR (By similarity). Interacts with LRP1 (PubMed:15272003). Interacts with APLP1 (via NPXY motif) (By similarity). Interacts with DAB2IP (By similarity).Post-translational Modifications: Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons. Also phosphorylated on Ser-524 independently of reelin signaling.Sim |
| Immunogen | Immunogen: A synthesized peptide derived from human Dab1 around the phosphorylation site of Tyr220. Tissue Specificity: Mainly expressed in brain. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Bovine (100%), Horse (92%), Sheep (92%), Rabbit (100%), Dog (100%), Xenopus (82%) |
| Other Names | [Dab 1; Dab reelin signal transducer 1; Dab, reelin signal transducer, homolog 1 (Drosophila); Dab1; DAB1_HUMAN; Disabled homolog 1; Disabled homolog 1 Drosophila; Scm; Scr; Scrambler; Yot; Yotari] |
| Gene, Accession # | [Dab1], Gene ID: 1600, NCBI: NP_066566.3, UniProt: O75553 |
| Catalog # | MBS9600663 |
| Price | $240, $280 |
| Order / More Info | Phospho-Dab1 (Tyr220) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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