Phospho-GSK3-S9 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-GSK3-S9 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Glycogen synthase kinase-3 (GSK-3) was initially identified as an enzyme that regulates glycogen synthesis in response to insulin (1). GSK-3 is a ubiquitously expressed serine/threonine protein kinase that phosphorylates and inactivates glycogen synthase. GSK-3 is a critical downstream element of the PI3K/Akt cell survival pathway whose activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3alpha and Ser9 of GSK-3beta (2,3). GSK-3 has been implicated in the regulation of cell fate in Dictyostelium and is a component of the Wnt signaling pathway required for Drosophila, Xenopus, and mammalian development (4). GSK-3 has been shown to regulate cyclin D1 proteolysis and subcellular localization (5). |
| Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding S9 of human GSK3 Calculated Molecular Weight: 46kDa |
| Other Names | [Phospho-GSK3B-S9: GSK3B; GSK 3 beta; GSK3B 216P; GSK3A B; gsk3beta], [GSK3B; GSK3B; GSK-3 beta] |
| Gene, Accession # | [GSK3B], Gene ID: 2932, NCBI: P49841.2, UniProt: P49841 |
| Catalog # | MBS125636 |
| Price | $235, $350, $525 |
| Order / More Info | Phospho-GSK3-S9 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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