EPHA1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEPHA1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of total EPHA1protein. Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. P
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human EPHA1.
Other Names[EC 2.7.10.1; EPA1; EPH; EPHT; EPHT1]
Gene, Accession #[EPHA1], Gene ID: 2041, NCBI: NP_005223.4, UniProt: P21709
Catalog #MBS9405401
Price$200, $255
Order / More InfoEPHA1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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