GCLM Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGCLM
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: GCLM antibody detects endogenous levels of total GCLM. Description: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.Subunit Structure: Heterodimer of a catalytic heavy chain and a regulatory light chain.Similarity: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
ImmunogenImmunogen: A synthesized peptide derived from human GCLM Tissue Specificity: In all tissues examined. Highest levels in skeletal muscle. Predicted Cross Reactivity: Pig, Bovine, Rabbit Similarity: Pig (100%), Bovine (100%), Rabbit (100%)
Other Names[Gamma ECS regulatory subunit; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; GCLM; GCS light chain; GLCLR; Glutamate cysteine ligase regulatory subunit; Glutamate--cysteine ligase modifier subunit; Glutamate--cysteine ligase regulatory subunit; GSC light chain; GSH0_HUMAN]
Gene, Accession #[GCLM], Gene ID: 2730, NCBI: NP_001295182.1, UniProt: P48507
Catalog #MBS9607906
Price$240, $280
Order / More InfoGCLM Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLi L, Sun HY, Liu W, Zhao HY, Shao ML; Journal: Food Chem Toxicol. Silymarin protects against acrylamide-induced neurotoxicity via Nrf2 signalling in PC12 cells. Zou Y, Wang J, Peng J, Wei H; Journal: Oxid Med Cell Longev. Oregano Essential Oil Induces SOD1 and GSH Expression through Nrf2 Activation and Alleviates Hydrogen Peroxide-Induced Oxidative Damage in IPEC-J2 Cells.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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