NR4A1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNR4A1
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: NR4A1 antibody detects endogenous levels of total NR4A1. Function: Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.Subunit Structure: Binds DNA as a monomer (By similarity). Interacts with GADD45GIP1. Interacts with STK11.Post-translational Modifications: Phosphorylated at Ser-351 by RPS6KA1 and RPS6KA3 in response to mitogenic or stress stimuli. Acetylated by p300/CBP, acetylation i
ImmunogenImmunogen: A synthesized peptide derived from human NR4A1 Subcellular Location: Nucleus. Tissue Specificity: Fetal muscle and adult liver, brain and thyroid. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (85%), Bovine (92%), Horse (92%), Sheep (92%), Rabbit (92%), Dog (85%)
Other Names[Early response protein NAK1; GFRP 1; GFRP; GFRP1; Growth factor inducible nuclear protein N10; Growth Factor Inducible Nuclear Protein NP10; Growth Factor Response Protein 1; Hbr1; HMR; Hormone Receptor; MGC9485; N10; N10 nuclear protein; NAK 1; NAK1; Nerve growth factor IB nuclear receptor variant 1; NGFIB; NP 10; NP10; NR4A1; NR4A1_HUMAN; Nuclear hormone receptor NUR/77; Nuclear Hormone Receptor TR3; Nuclear receptor subfamily 4 group A member 1; NUR77; NUR77, mouse, homolog of; Orphan nuclear receptor HMR; Orphan nuclear receptor NR4A1; Orphan nuclear receptor TR3; Orphan receptor tr3; Receptor NGFIB; ST 59; ST-59; ST59; Steroid receptor TR3; Testicular receptor 3; TR 3; TR3; TR3 orphan receptor]
Gene, Accession #[NR4A1], Gene ID: 3164, NCBI: NP_001189162.1, UniProt: P22736
Catalog #MBS9608396
Price$240, $280
Order / More InfoNR4A1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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