Neuropilin-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNeuropilin-1
Clonepolyclonal
Host Speciesn/a
Reactive Speciesmouse
Isotypen/a
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC)
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DescriptionThis antibody is produced by immunizing mouse with recombinant protein Neuropilin-1. Neuropilin-1 is a single-pass type I membrane protein, which has two isoforms. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. The soluble isoform 2 binds VEGF-165 (vascular endothelial growth factor165) and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. Its expression has an averse effect on blood vessel number and integrity.
Immunogenn/a
Other Names[neuropilin-1 isoform 1; Neuropilin-1; neuropilin-1; neuropilin 1; A5 protein; CD_antigen: CD304], [Nrp1; Nrp1; Nrp; NP-1; Npn1; NPN-1; C530029I03; Nrp]
Gene, Accession #Gene ID: 18186, NCBI: NP_032763.2, UniProt: P97333
Catalog #MBS850768
Price$280
Order / More InfoNeuropilin-1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Neuropilin-2 and neuropilin-1 are receptors for the 165-amino acid form of vascular endothelial growth factor (VEGF) and of placenta growth factor-2, but only neuropilin-2 functions as a receptor for the 145-amino acid form of VEGF.Gluzman-Poltorak Z., Cohen T., Herzog Y., Neufeld G.J. Biol. Chem. 275:18040-18045(2000). 2. Neuropilin is a receptor for the axonal chemorepellent semaphorin III.He Z., Tessier-Lavigne M.Cell 90:739-751(1997).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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