Robo1 (C-Terminal Region) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRobo1 (C-Terminal Region)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA), Immunocytochemistry (ICC)
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DescriptionThis antibody was affinity purified using Robo1 (C-terminal region) peptide. The purified antibody detects a 180 kDa* band corresponding to Robo1 in Western blots of human HepG2 and HUVEC cells, as well as mouse C2C12 cells. The Robo family of repulsive guidance receptors (Robo1-4) have important roles in controlling axon guidance and cell migration. These receptors are members of the immunoglobulin (Ig) superfamily and consist of an ectodomain with five Ig domains and three fibronectin type III repeats, a single transmembrane domain, and a long cytoplasmic tail that contains four blocks of conserved cytoplasmic sequences. In Drosophila, mutations in Robo, and its midline-expressed ligand Slit, result in too many axons crossing and staying
ImmunogenImmunogen: Robo1 synthetic peptide (coupled to carrier protein) corresponds to amino acids in the C-terminal region of human Robo1. This sequence has significant homology to the same region in rat and mouse Robo1, and has low homology to other Robo family members.
Other Names[roundabout; DUTT1], [ROBO1; ROBO1; SAX3; DUTT1; DUTT1]
Gene, Accession #[Robo1], Gene ID: 6091, NCBI: NP_002932.1, UniProt: Q9Y6N7
Catalog #MBS474134
Price$325
Order / More InfoRobo1 (C-Terminal Region) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKidd, T. et al. (1998) Cell 92:205.Bashaw, G.J. et al. (2000). Cell 101:703.Yang, L. & Bashaw, G.J. (2006). Neuron 52:595.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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