Sortilin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySortilin
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken, Xenopus
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: Sortilin Antibody detects endogenous levels of Sortilin. Description: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the fo
ImmunogenImmunogen: A synthesized peptide derived from human Sortilin. Tissue Specificity: Expressed in brain and prostate (at protein level). Expressed at high levels in brain, spinal cord, heart, skeletal muscle, thyroid, placenta and testis. Expressed at lower levels in lymphoid organs, kidney, colon and liver.
Other Names[100 kDa NT receptor; Glycoprotein 95; Gp 95; Gp95; LDLCQ6; Neurotensin receptor 3; NT 3; NT3; NTR 3; NTR3; OTTHUMP00000013784; SORT 1; SORT_HUMAN; SORT1 (gene name); Sort1; Sortilin 1; Sortilin]
Gene, Accession #[SORT1], Gene ID: 6272, NCBI: Q99523.3, UniProt: Q99523
Catalog #MBS9611497
Price$240, $280
Order / More InfoSortilin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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