UNG Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityUNG
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
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DescriptionWhen misincorporation or cytosine deamination positions the RNA nucleotide uracil into DNA, uracilDNA gycosylase (UDG) excises the uracil via a repair enzymatic pathway. This is done by cleaving the NC1' gylcosylic bond between the base and deoxyribose, in both single and doublestranded DNA. While initiating the first steps of DNA repair, UDG undergoes a conformational change from the open unbound state to the closed DNAbound state, creating a catalytic center. The bound UDG effectively flips the uridine nucleotide into the catalyic center and cleaves the glycosylic bond to excise the uracil. The opentoclosed conformation change is centered on a B zipper in the UDG. UDG alters the orientation electron orbitals to favor electron transpos
ImmunogenImmunogen: A synthetic peptide of human UNG
Other Names[UNG; UNG; DGU; DKFZp781L1143; HIGM4; UDG; UNG1; UNG15; UNG2; UracilDNA glycosylase], [UNG; UNG; DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15; DGU; UNG1; UNG15; UDG]
Gene, Accession #Gene ID: 7374, NCBI: NP_003353.1, UniProt: P13051
Catalog #MBS128010
Price$200, $275, $430
Order / More InfoUNG Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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