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Antigenic Specificity | Phospho-Erk1/2 Pathway Sampler Kit |
Clone | n/a |
Host Species | n/a |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 1 kit |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs, such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines, and research investigators consider it an important target in the diagnosis and treatment of cancer. Upon stimulation, a sequential three-part protein kinase cascade is initiated, consisting of a MAP kinase kinase kinase (MAPKKK or MAP3K), a MAP kinase kinase (MAPKK or MAP2K), and a MAP kinase (MAPK). Multiple p44/42 MAP3Ks have been identified, including mem |
Immunogen | n/a |
Other Names | [Erk1/2; Mitogen-activated protein kinase] |
Gene, Accession # | [Erk1/2], NCBI: AEE81046.1 |
Catalog # | MBS2550028 |
Price | $345 |
Order / More Info | Phospho-Erk1/2 Pathway Sampler Kit Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |