Mcl-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMcl-1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, monkey
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.2 mg/ml
ApplicationsWestern Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC)
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DescriptionBackground: Mcl-1 (Myeloid cell leukemia-1) is a 37 kDa Bcl-2-related protein with an apparent molecular weight of 43 kDa on SDS-PAGE. Mcl-1 was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-beta1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reag
ImmunogenImmunogen: Synthetic peptide corresponding to residues surrounding amino acid 131 of human Mcl-1
Other Names[MCL1L; mcl1/EAT; MGC1839; MGC104264; TM; MCL1S; EAT], [MCL1; MCL1; TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; BCL2L3; Bcl2-L-3]
Gene, Accession #[Mcl-1], Gene ID: 4170, NCBI: NP_001184249.1, UniProt: Q07820
Catalog #MBS841378
Price$150, $290
Order / More InfoMcl-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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