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Antigenic Specificity | Human MCL1 / MCL 1 |
Clone | [2E11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.05 mL |
Concentration | 0.89 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human MCL 1. Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. |
Immunogen | Immunogen Description: Full length human recombinant protein of human MCL1 (NP_068779) produced in HEK293T cell. |
Other Names | [MCL1 / MCL 1 (clone 2E11) IHC-plus; MCL1; BCL2L3; Bcl-2-like protein 3; Bcl-2-related protein EAT/mcl1; Bcl2-L-3; MCL1S; MCL1L; Myeloid cell leukemia ES; MCL 1; MCL1-ES; TM; EAT; Mcl-1; Human MCL1; MCL 1], [MCL 1] |
Gene, Accession # | [MCL1], Gene ID: 4170, NCBI: NP_068779.1, UniProt: Q07820 |
Catalog # | MBS249129 |
Price | $530 |
Order / More Info | Human MCL1 / MCL 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |