Edit |   |
---|---|
Antigenic Specificity | Human VON WILLEBRAND FACTOR |
Clone | [RFF-VIII R/1] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.5 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | ELISA (EIA), Immunohistology Paraffin*, Protein Purification (PP), Radioimmunoassays (RIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human von Willebrand factor antibody, clone RFF-VIII R/1 recognizes human von Willebrand factor (vWF), also known as Factor VIII related antigen, a blood glycoprotein involved in blood coagulation. It stabilises circulating Factor VIII by binding to it and protecting it from cleavage and delivers it to sites of vascular injury. vWF also promotes the adhesion of platelets to sites of vascular damage by forming a molecular bridge between collagen on exposed endothelial cells and the GPIb binding sites of platelets circulating in the blood. vWF circulates in the blood as large multimers, with each monomer (250kDa) containing a number of specific domains. Hereditary or acquired defects in vWF lead to von Willebrand disease (vWD), cha |
Immunogen | Immunogen: Human Factor VIII complex partially purified from Factor VIII concentrate. Histology Positive Control Tissue: Human tonsil, thymus, liver, spleen or kidney. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [von Willebrand factor preproprotein; von Willebrand factor; von Willebrand factor; coagulation factor VIII VWF; von Willebrand factor; von Willebrand antigen II], [VWF; VWF; VWD; F8VWF; F8VWF; vWF] |
Gene, Accession # | Gene ID: 7450, NCBI: NP_000543.2, UniProt: P04275 |
Catalog # | MBS219591 |
Price | $515 |
Order / More Info | Human VON WILLEBRAND FACTOR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |