CD34 (Endothelial Cell Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD34 (Endothelial Cell Marker)
Clone[Q-bend 10]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size1 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin)
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DescriptionSpecificity: Q-bend 10 reacts with a single chain transmembrane glycoprotein with a molecular weight of 105-120kD, which is selectively expressed on Human lymphoid, myeloid haemapoietic progenitor cells and also expressed on vascular endothelium. CD34 is a single chain transmembrane glycoprotein with a molecular weight of 105-120kD. The antigen is selectively expressed on Human lymphoid, myeloid haemapoietic progenitor cells and expressed on vascular endothelium. This antibody is of value in the study of benign and malignant vascular tumors as well as in the characterization of leukemias.
ImmunogenSource Note: Q-bend 10 is a Mouse monoclonal IgG1 antibody derived by fusion of p3-NS-0 Mouse myeloma cells with spleen cells from a BABL/c Mouse immunized with an immunogenic fraction isolated from Human leucocytes.
Other Names[CD34; CD34 antigen; hematopoietic progenitor cell antigen CD34; CD34 antigen; OTTHUMP00000034733; OTTHUMP00000034734; CD34 molecule], [CD34; CD34; CD34]
Gene, Accession #Gene ID: 947, UniProt: Q3C1E7
Catalog #MBS570024
Price$390
Order / More InfoCD34 (Endothelial Cell Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesRamani P., Bradley N.J., Fletcher C.D. (1990). QBEnd/10, a new monoclonal antibody to endothelium: Assessment of its diagnostic utility in paraffin section. Histopathol. 17, 237-242. Fletcher, C.D., Ramani, P. (1990) QBEnd/10: a useful, but by no means specific, marker of Kaposi's sarcoma. J Pathol. 162, 273-4. Grimsley P.G., Amos, T.A., Gordon, M.Y. and Greaves, M.F. (1993) Rapid positive selection of CD34 cells using magnetic microspheres coated with monoclonal antibody QBEND/10 linked via a cleavable disulphide bond. Leukemia 7, 898-908. Lopez-Graniel, C.M., Tamez de Leon, D., Meneses-Garcia, A., Gomez-Ruiz, C., Frias-Mendivil, M., Granados-Garcia and M., Barrera-Franco, J.L. (2001) Tumor angiogenesis as a prognostic factor in oral cavity carcinomas. J Exp Clin Cancer Res. 20, 463-8. Allen, J.E. and Henshaw, D.L. (2001) An in situ study of CD34( ) cells in Human fetal bone marrow.Br J Haematol. 114, 201-10.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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