TLR7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTLR7
Clone[4F4]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, k
FormatProtein G purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionTLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity by recognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Human TLR7 (hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7,8 genes are located on the sex chromosome X. hTLR7 may play an important role in detecting and combating viral infections.
ImmunogenImmunogen: Recombinant human TLR7 (451-500aa) purified from E. coli
Other Names[toll-like receptor 7; PRO285; UNQ248; tlr 7], [TLR7; TLR7; TLR7-like]
Gene, Accession #[TLR7], Gene ID: 51284, NCBI: NP_057646, UniProt: Q9NYK1
Catalog #MBS200017
Price$240, $315
Order / More InfoTLR7 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLee J., et al. (2003) Proc. Natl. Acad. Sci. USA. 100, 6646-6651; Crozat K., et al. (2004) Proc. Natl. Acad. Sci. USA. 101, 6835-6836; Muzio M., et al. (1998) J. Exp. Med. 187, 2097-2101; Horng T., et al. (2002) Nature 420, 329-333
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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