TLR4 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-TLR4 antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | TLR4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | ATTO 633 conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects ~75-80kDa when tested against partial recombinant mouse TLR4 (extra-cellular portion plus His-tag). Scientific Background: The Toll-like receptor (TLR) family in mammal comprises a family of trans-membrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and 1L-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylo-genetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). Amount this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TL |
| Immunogen | n/a |
| Other Names | [ARMD10; CD284; TLR 4; TOLL; Toll like receptor 4], [TLR4; TLR4; TOLL; CD284; TLR-4; ARMD10] |
| Gene, Accession # | Gene ID: 7099, NCBI: NP_612564.1, UniProt: O00206 |
| Catalog # | MBS804980 |
| Price | $405 |
| Order / More Info | TLR4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1.JMuzio M., Natoli G., Saccan S., Levrero M., and Mantovani A. (1998) J. Exp. Med. 187: 2097-2101. 2. Medzhitov R. and Janeway C.A (1997). Cell 91: 295-298. 3. Chuang T.H. and Ulevitch R.J. (2001) Biochim. Biophys. Acta 1518 (1-2): 157-161). 4. Takeuchi O., et al. (1999) Immunity 11: 443. 5. Poltorak A., Riccardi-Castagnoli P., Citterio S., and Butler B. (2000) Proc. Natl. Acad. Sci USA 97: 2163-2167. 6. Medzhitov R., Preston-Hurlburt P. and Janeway C.A. (1997) Jr. Nature 388 (6640): 394-397. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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