PSRC1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPSRC1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: PSRC1 antibody detects endogenous levels of total PSRC1. Description: This gene encodes a proline-rich protein. Studies of this gene and the related mouse gene suggest that this gene is regulated by p53 and may participate in p53-mediated growth suppression. The encoded protein may function as a microtubule destabilizing protein that controls spindle dynamics and mitotic progression by recruiting and regulating microtubule depolymerases. At least one genetic variation in this gene has been associated with decreased serum levels of low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding different isoforms have been described.Function: Required for normal progression through mitosis. Required f
ImmunogenImmunogen: A synthesized peptide derived from human PSRC1 Subcellular Location: Cytoplasm. Cytoplasm > Cytoskeleton > Spindle. Cytoplasm > Cytoskeleton > Spindle Pole. Detected at the mitotic spindle and spindle poles. Diffusely distributed throughout the cell during interphase. Tissue Specificity: Widely expressed in adult and fetal tissues, with highest expression in the adult brain and fetal thymus. Not detected in adult skeletal muscle. Predicted Cross Reactivity:
Other Names[DDA3; DDA3, mouse, homolog of; Differential display and activated by p53; FP3214; OTTHUMP00000013785; OTTHUMP00000013786; p53-regulated DDA3; Proline/serine-rich coiled-coil 1; Proline/serine-rich coiled-coil protein 1; PSRC1; PSRC1_HUMAN]
Gene, Accession #[PSRC1], Gene ID: 84722, NCBI: NP_001005290.1, UniProt: Q6PGN9
Catalog #MBS9608003
Price$240, $280
Order / More InfoPSRC1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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