RAB7A Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RAB7A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: RAB7A antibody detects endogenous levels of total RAB7A. Description: Rab7 and Rab9 are members of the Ras superfamily of small RabGTPases (1). Both proteins are located in late endosomes, but exert different functions. Rab7 associates with the RIPL effector protein to control membrane trafficking from early to late endosome and to lysosomes (2, 3). Rab7 also helps to regulate growth receptor endocytic trafficking and degradation (3, 4), and maturation of phagosome and autophagic vacuoles (4-6). Rab9 interacts with its effector proteins p40 and TIP47 (7, 8) to promote the MPR (mannose 6-phosphate receptor)-associated lysosomal enzyme transport between late endosomes and the trans Golgi network (9, 10).Function: Key regulato |
| Immunogen | Immunogen: A synthesized peptide derived from human RAB7A Subcellular Location: Late endosome. Lysosome. Cytoplasmic Vesicle > Phagosome. Melanosome. Cytoplasmic Vesicle > Phagosome Membrane. Co-localizes with OSBPL1A at the late endosome. Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts. Recruited to phagosomes containing S.aureus or Mycobacterium. Tissue Specificity: Widely expressed; high expression found in skeletal muscle. |
| Other Names | [CMT2B; PRO2706; PSN; RAB7, member RAS oncogene family; RAB7A; RAB7A, member RAS oncogene family; RAB7A_HUMAN; Ras associated protein RAB7; Ras related protein Rab7; Ras related protein Rab7a; Ras-related protein Rab-7a] |
| Gene, Accession # | [RAB7A], Gene ID: 7879, NCBI: NP_004628.4, UniProt: P51149 |
| Catalog # | MBS9606947 |
| Price | $240, $280 |
| Order / More Info | RAB7A Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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