CAV1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCAV1
Clone[AT4C1]
Host SpeciesMouse
Reactive Specieshuman, rat
IsotypeIgG2b, k
FormatProtein G purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)
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DescriptionThe identification of caveolin-1 (CAV1) as the main structural component of caveolae, together with the finding that CAV1 might serve as a molecular organizer for membrane multiprotein complexes involved in cellular traffic, endo-and transcytosis, cell adhesion and signal transduction prompted a new impulse in the research on these intracellular organells. One of the properties of CAV1 was its insolubility in cold non-ionic detergents together with apical markers in epithelial cell. Also, cholesterol is essential for caveolae formation and maintenance, and caveolae structure is highly sensitive to cholesterol depletion or treatment with cholesterol binding drugs. CAV1 tightly and specifically binds free cholesterol and artificial cholestero
ImmunogenImmunogen: Recombinant human CAV1 (1-104aa) purified from E. coli
Other Names[VIP 21; CAV; CAV 1; CAV1; caveolae protein 22 kD; caveolin 1 alpha isoform; caveolin 1 beta isoform; Caveolin 1 caveolae protein 22kDa; Caveolin1; cell growth-inhibiting protein 32; MSTP085; OTTHUMP00000025031; VIP 21; VIP21], [CAV1; CAV1; CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085; CAV]
Gene, Accession #[CAV1], Gene ID: 857, NCBI: NP_001744, UniProt: Q03135
Catalog #MBS200195
Price$240, $315
Order / More InfoCAV1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesVan Meer, G., et al. (2008) Nat Rev Mol Cell Biol. 9: 112-124; Todeschini, R.A. et al. (2008) Biochim Biophy Acta 1780: 421-433; Lajoie, P et al. (2007) J Cell Mol Med 11: 644-653
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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