WASP / N-WASP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityWASP / N-WASP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA, Western Blot
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DescriptionThis antibody detects a 63 kDa* protein corresponding to the molecular mass of WASP on SDS-PAGE immunoblots of Jurkat cell lysate. In rat brain, A431, and SKN-SH cells, this antibody detects a 65 kDa* protein corresponding to the molecular mass of N-WASP. Members of the Wiskott-Aldrich sydrome protein (WASP) family regulate the formation of actin-based cell structures in many cell types. These proteins contain C-terminal actin-binding domains that can stimulate actin polymerization. In addition, these proteins bind the ARP2/3 complex, which can nucleate actin polymerization at sites that lead to branched actin structures. WASP is expressed primarily in hematopoietic cells, while its homolog N-WASP is widely expressed. These proteins have 48
ImmunogenImmunogen: A synthetic peptide (coupled to KLH) corresponding to a region near the C-terminus of human WASP. This sequence is highly homologous with a similar region in human N-WASP.
Other Names[WASP / N-WASP; Neural Wiskott-Aldrich syndrome protein; WASL], [WASL; WASL; NWASP; N-WASP; MGC48327; DKFZp779G0847]
Gene, Accession #Gene ID: 8976, NCBI: NP_003932.3, UniProt: O00401
Catalog #MBS472066
Price$385
Order / More InfoWASP / N-WASP Antibody from MYBIOSOURCE INC.
Product Specific References• Cory, G.O. et al. (2003) Mol Cell. 11(5):1229-39.• Higgs, H.N. & Pollard, T.D. (2001) Annu Rev Biochem 70:649-676.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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