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Antigenic Specificity | PKCD (Phospho-Tyr64) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of PKCD only when phosphorylated at tyrosine 64. Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Wie SM, et al. (2014)J Biol Chem. Adwan TS, et al. (2011)J Biol Chem 286, 35716-24. Lomonaco SL, et al. (2008) J Biol Chem 28 |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Tyrosine 64 (H-I-Y(p)-E-G) derived from Human PKCD. |
Other Names | [KPCD; PKC-delta; PRKCD; kinase PKC-delta; nPKC-delta] |
Gene, Accession # | [PKCD], Gene ID: 5580, NCBI: NP_006245.2, UniProt: Q05655 |
Catalog # | MBS9411343 |
Price | $200, $255 |
Order / More Info | PKCD (Phospho-Tyr64) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |