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Antigenic Specificity | Src Antibody Sampler Kit |
Clone | n/a |
Host Species | n/a |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 1 kit |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells. Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy- terminal tail by Csk renders the enzyme less active. Lyn is a member of the Src family that is predominantly expressed in hematopoietic cells. Lyn participates in signaling from multiple cell surface receptors such as the B cell Ag receptor (BCR) and CD40. Lck is essential for T-lymphocyte activation and different |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [Src] |
Catalog # | MBS2550034 |
Price | $295 |
Order / More Info | Src Antibody Sampler Kit Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |