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Antigenic Specificity | Human TFRC |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse transferrin receptor protein 1, also known as transferrin receptor, Trfr, p90, CD71 and TFRC, is a single-pass type II membrane protein which belongs to the peptidase M28 family and M28B subfamily. TFRC/CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC/CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC/CD71 represents a marker of malignant tran |
Immunogen | Immunogen: Recombinant Human Transferrin Receptor/TFRC/CD71 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
Other Names | [transferrin receptor protein 1 isoform 2; Transferrin receptor protein 1; transferrin receptor protein 1; transferrin receptor; T9; p90; CD_antigen: CD71] |
Gene, Accession # | [TFRC ], Gene ID: 7037 |
Catalog # | MBS2544144 |
Price | $215, $330, $500 |
Order / More Info | Human TFRC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |