Edit |   |
Antigenic Specificity | Claudin 5 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | rat. predicted to work with: human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Claudin-5(CLDN5) detection. Tested with WB in Human;Rat. Background: Claudin-5(CLDN5) also known as BEC1, is a protein that in humans is encoded by the CLDN5 gene. By use of yeast artificial chromosomes, Claudin-5 is localized between polymorphic markers D22S944 and D22S941 on chromosome 22q11, both of which are deleted in more than 80% of VCFS patients. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. What's more, it plays a major role |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 5(191-218aa RPDLSFPVKYSAPRRPTATGDYDKKNYV), different from the related mouse sequence by three amino acids and from the related rat sequence by four amino acids. Ig Type: Rabbit IgG |
Other Names | [Claudin-5; Androgen withdrawal and apoptosis induced protein RVP1 like; AWAL; BEC 1; BEC1; Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); Claudin-5; Claudin5; CLD5_HUMAN; CLDN 5; CLDN5; CPETR L1; CPETRL 1; CPETRL1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; Transmembrane protein deleted in velocardiofacial syndrome; claudin 5], [CLDN5; CLDN5; AWAL; BEC1; TMVCF; CPETRL1; AWAL; TMVCF; TMDVCF] |
Gene, Accession # | Gene ID: 7122, NCBI: NP_001124333.1, UniProt: O00501 |
Catalog # | MBS178310 |
Price | $280 |
Order / More Info | Claudin 5 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Sirotkin, H., Morrow, B., Saint-Jore, B., Puech, A., Das Gupta, R., Patanjali, S. R., Skoultchi, A., Weissman, S. M., Kucherlapati, R. Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome. 2. Peacock RE, Keen TJ, Inglehearn CF (Mar 1998). Analysis of a human gene homologous to rat ventral prostate.1 protein. Genomics 46 (3): 443-9. 3. Entrez Gene: CLDN5 claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) |