Phospho-ERK8(Thr175+Tyr177) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-ERK8(Thr175+Tyr177) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-ERK8(Thr175+Tyr177) antibody detects endogenous levels of ERK8 only when phosphorylated at Threonine 175 and Tyrosine 177. Description: ERK7 is phosphorylates MBP in vitro. Interacts with CSK/c-Src, ABL1 and RET. 3 isoforms of the human protein are produced by alternative splicing.Function: In vitro, phosphorylates MBP.Subunit Structure: Interacts with CSK/c-Src, ABL1, RET and TGFB1I1.Post-translational Modifications: Dually phosphorylated on Thr-175 and Tyr-177, which activates the enzyme. Autophosphorylated on threonine and tyrosine residues in vitro. Ubiquitinated. Ubiquitination may allow its tight kinase activity regulation and rapid turnover. May be ubiquitinated by a SCF E3 ligase (By similarity). |
| Immunogen | Immunogen: A synthesized peptide derived from human ERK8 around the phosphorylation site of Threonine 175 and Tyrosine 177 Tissue Specificity: Widely expressed with a maximal expression in lung and kidney. |
| Other Names | [ERK-7; ERK-8; ERK7; ERK8; Extracellular regulated kinase 8 delta; Extracellular signal regulated kinase 8; Extracellular signal-regulated kinase 7; Extracellular signal-regulated kinase 8; MAP kinase 15; MAPK 15; Mapk15; Mitogen activated protein kinase 15; Mitogen-activated protein kinase 15; MK15_HUMAN] |
| Gene, Accession # | [ERK8], Gene ID: 225689, NCBI: NP_620590.2, UniProt: Q8TD08 |
| Catalog # | MBS9600010 |
| Price | $240, $280 |
| Order / More Info | Phospho-ERK8(Thr175+Tyr177) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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