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Antigenic Specificity | MAG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MAG is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR. It is thought to be involved in the process of myelination. MAG is a sialic acid-binding SIGLEC protein and is a functional ligand for the NOGO receptor.The MAG gene is mapped on 19q13.12. Cleavage of GPI-linked proteins from axons protects growth cones from MAG-induced collapse, and dominant-negative NgR eliminates MAG inhibition of neurite outgrowth. MAG-resistant embryonic neurons were rendered MAG-sensitive by expression of NgR. MAG binds specifically to an NgR-expressing cell line in a GPI-dependent and sialic acid-independent manner. Experiments blocking NgR from interacting with MAG prevented |
Immunogen | Immunogen: MAG antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human MAG, identical to the related rat and Rabbit sequences, as the immunogen |
Other Names | [Affinity Purified Rabbit MAG; MAG; MAG; SIGLEC4A; Myelin associated glycoprotein] |
Gene, Accession # | [MAG], Gene ID: 4099 |
Catalog # | MBS5313038 |
Price | $345 |
Order / More Info | MAG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |