Edit |   |
---|---|
Antigenic Specificity | IGF1 Receptor Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: IGF1R(Insulin-like Growth Factor 1 (IGF-1) Receptor) is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by a hormone called Insulin-like growth factor 1 (IGF-1) and by a related hormone called IGF-2. It belongs to the large class of tyrosine kinase receptors. The IGF1R gene is mapped on 15q26.3. IGF-1 plays an important role in growth and continues to have anabolic effects in adults - meaning that it can induce hypertrophy of skeletal muscle and other target tissues. Using a yeast 2-hybrid system, it was identified a regulatory subunit of phosphatidylinositol (PI) 3-kinase, PIK3R3, as a binding partner of IGF1R. Functional interaction between BRCA1 and SP1 in the regulation of the |
Immunogen | Immunogen: E Coli-derived mouse IGF1 Receptor recombinant protein (Position: E31-K257). Subcellular Localization: Cell membrane; Single-pass type I membrane protein. |
Other Names | [Insulin-like growth factor 1 receptor; 2.7.10.1; Insulin-like growth factor I receptor; IGF-I receptor; CD221; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Igf1r] |
Gene, Accession # | [Igf1r], Gene ID: 16001, NCBI: NP_034643.2, UniProt: Q60751 |
Catalog # | MBS1750322 |
Price | $315 |
Order / More Info | IGF1 Receptor Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |