Phospho- STAT3 (pTyr 705) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho- STAT3 (pTyr 705)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse, dog, bovine, chicken
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
ConcentrationSize: 100 ug/200 ul
ApplicationsELISA, Western Blot, Immunohistochemistry
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DescriptionThis antibody recognizes STAT3 (pY705) with a phosphorylated sites of Tyr705. It does not cross-react with non-phosphospecific peptide. STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a lignad binding to its cell surface receptor. The phosphorylation of STAT3 induces STAT dimerization, nuclear translocation and DNA binding. Stat3 is constitutively activated in a number of human tumors. Stat3- activated transcription seems to be regulated by serine phosphorylation at Ser727 and tyrosine phosphorylation at Tyr705.
ImmunogenAntigen Preparation: A synthetic peptide surrounding to the epitope -APYLK-- with phosphorylation sites at Tyr705 of STAT3 protein from human, mouse, rat, chicken dog and bovine origins.
Other Names[Rabbit Phospho-STAT3 (pY705); Signal transducer and activator of transcription 3 (STAT3)], [STAT3; STAT3; APRF; HIES; FLJ20882; MGC16063; APRF]
Gene, Accession #[STAT3 (pY705)], Gene ID: 6774, NCBI: NP_644805.1, UniProt: P40763
Catalog #MBS462114
Price$285
Order / More InfoPhospho- STAT3 (pTyr 705) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesRitsuko Matsuo et al. A new expression cloning strategy for isolation of substrate-specific kinases by using phosphorylation site-specific antibody. Journal of Immunological Methods. Volume 247, Issues 1-2, 1 January 2001, Pages 141-151
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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