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Antigenic Specificity | RAT ALPHA SYNUCLEIN (pSer129) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine (expected from sequence), dog (expected from sequence), human (expected from sequence), mouse (expected from sequence), primate (expected from sequence) |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB)* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item specifically recognises rat alpha synuclein when phosphorylated at Ser129. Alpha synuclein is a 140 amino acid, 15kDa protein seen predominantly in the neocortex, hippocampus, substantia nigra, thalamus and cerebellum. Its normal cellular function has not been definitively determined, but it is thought to be involved in the regulation of neuronal plasticity, dopamine neurotransmission and other membrane-associated processes at the presynaptic terminal. Alpha synuclein is normally a soluble, unfolded protein, but it can aggregate at high concentrations to form insoluble fibrils which, in association with other proteins such as ubiquitin, neurofilament protein and alpha B crystalline, form Lewy bodies. Lewy bodies are a hallmark pat |
Immunogen | Immunogen: Synthetic phosphopeptide corresponding to amino acid sequence surrounding phosphorylated serine 129 of Alpha Synuclein. Buffer Solution: 10mM Hepes pH7.5, 150mM NaCl Antiserum Preparation: Antisera to Alpha Synulein (pSer129) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Rat |
Other Names | [alpha-synuclein; Alpha-synuclein; alpha-synuclein; synuclein, alpha (non A4 component of amyloid precursor)], [Snca; Snca] |
Gene, Accession # | Gene ID: 29219, NCBI: NP_062042.1, UniProt: P37377 |
Catalog # | MBS222961 |
Price | $550 |
Order / More Info | RAT ALPHA SYNUCLEIN (pSer129) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |