Cleaved Caspase-9 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCleaved Caspase-9
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunoprecipitation (IP)
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DescriptionInvolved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
ImmunogenImmunogen: A synthesized peptide derived from human cleaved Caspase-9
Other Names[MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; Caspase 9 Dominant Negative]
Gene, Accession #[CASP9], Gene ID: 842, NCBI: NP_001220.2, UniProt: P55211
Catalog #MBS8542702
Price$280
Order / More InfoCleaved Caspase-9 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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