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Antigenic Specificity | CNTFR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011] |
Immunogen | Immunogen: Rabbit polyclonal CNTFR antibody was raised against a 14 amino acid peptide from the internal residues of human CNTFR |
Other Names | [ciliary neurotrophic factor receptor subunit alpha preproprotein; Ciliary neurotrophic factor receptor subunit alpha; ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; CNTFR-alpha; ciliary neurotrophic factor receptor], [CNTFR; CNTFR] |
Gene, Accession # | [CNTFR], Gene ID: 1271, NCBI: NP_001193940.1 |
Catalog # | MBS416347 |
Price | $230 |
Order / More Info | CNTFR Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Rousseau,F., Gauchat,J.F., McLeod,J.G?A'et,al Inactivation of cardiotrophin-like cytokine, a second ligand for ciliary neurotrophic factor receptor, leads to cold-induced sweating syndrome in a patient. PNAS.2008;105 (35):10068-10073. |