N-WASP Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | N-WASP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects a 65 kDa* protein corresponding to the molecular mass of N-WASP on SDS-PAGE immunoblots of neonatal rat brain lysate. It is also detects 65 kDa* proteins in A431, human endothelial, and SKN-SH cells. It does not recognize the 63 kDa* WASP protein in Jurkat cell lysate. Members of the Wiskott-Aldrich sydrome protein (WASP) family regulate the formation of actin-based cell structures in many cell types. These proteins contain C-terminal actin-binding domains that can stimulate actin polymerization. In addition, these proteins bind the ARP2/3 complex, which can nucleate actin polymerization at sites that lead to branched actin structures. WASP is expressed primarily in hematopoietic cells, while its homolog N-WASP is wide |
| Immunogen | Immunogen: N-WASP synthetic peptide (coupled to KLH) corresponding to amino acid residues in the N-terminal region of human N-WASP. This N-WASP peptide sequence is 100% to rat and mouse N-WASP, and has low homology to the corresponding region in the human WASP sequence. |
| Other Names | [N-WASP; Neural Wiskott-Aldrich syndrome protein; WASL], [WASL; WASL; NWASP; N-WASP; MGC48327; DKFZp779G0847] |
| Gene, Accession # | Gene ID: 8976, NCBI: NP_003932.3, UniProt: O00401 |
| Catalog # | MBS472039 |
| Price | $385 |
| Order / More Info | N-WASP Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Cory, G.O. et al. (2003) Mol Cell. 11(5):1229-39.• Higgs, H.N. & Pollard, T.D. (2001) Annu Rev Biochem 70:649-676. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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