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Antigenic Specificity | UCP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: UCP1 antibody detects endogenous levels of total UCP1. Function: Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance (By similarity). Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane (PubMed:24196960). However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient |
Immunogen | Immunogen: A synthesized peptide derived from human UCP1 Subcellular Location: Mitochondrion Inner Membrane. Tissue Specificity: Brown adipose tissue. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog Similarity: Bovine (91%), Horse (91%), Sheep (91%), Rabbit (91%), Dog (91%) |
Other Names | [mitochondrial brown fat uncoupling protein; Mitochondrial brown fat uncoupling protein 1; SLC25A7; Solute carrier family 25 member 7; Thermogenin; UCP 1; UCP; UCP1; UCP1_HUMAN; uncoupling protein 1 (mitochondrial, proton carrier); Uncoupling protein 1] |
Gene, Accession # | [UCP1], Gene ID: 7350, NCBI: NP_068605.1, UniProt: P25874 |
Catalog # | MBS9608300 |
Price | $240, $280 |
Order / More Info | UCP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |