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Antigenic Specificity | TLR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis. |
Immunogen | Immunogen: TLR4 antibody was raised against a peptide corresponding to 15 amino acids near the amino-terminus of human TLR4. Buffer: TLR4 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TLR4; TOLL; CD284; TLR-4; ARMD10; Toll-like receptor 4; hToll; toll-like receptor 4], [TLR4; TLR4; TOLL; CD284; TLR-4; ARMD10] |
Gene, Accession # | [TLR4], Gene ID: 7099, NCBI: NP_612564, UniProt: O00206 |
Catalog # | MBS150782 |
Price | $375 |
Order / More Info | TLR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |