LC3B (Cleaved) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLC3B (Cleaved)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse. predicted cross reactivity with bovine samples.
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Immunofluoresence (IF)
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DescriptionPolyclonal antibody to detect LC3B in human and mouse samples. Background: Autophagy is an alternative process of proteasomal degradation for some long-lived proteins or organelles. Alterations in the autophagic-lysosomal compartment have been linked to neuronal death in many neurodegenerative disorders as well as in transmissible neuronal pathologies (prion diseases). Genetic studies in yeast have shown that Autophagy-defective Gene-8 (Atg-8) represents a specific marker for autophagy. Among the four families of mammalian Atg8-related proteins only LC3 (Microtubule-associated Protein1 Light Chain 3) is expressed at sufficient high levels and efficiently recruited to autophagic vesicles in cells and tissues. During autophagy the cytoplasmic
ImmunogenImmunogen: This Cleaved LC3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-122 amino acids from human Cleaved LC3B. Positive Control: ICC: U251 cells, IF: SY5Y cells
Other Names[MAP1LC3B; MAP1ALC3; Microtubule-associated proteins 1A/1B light chain 3B; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B light chain 3 B; Microtubule-associated protein 1 light chain 3 beta.], [MAP1LC3B; MAP1LC3B; LC3B; ATG8F; MAP1LC3B-a; MAP1A/1BLC3; MAP1ALC3; MAP1A/MAP1B LC3 B]
Gene, Accession #[LC3B], Gene ID: 81631, NCBI: NP_073729.1, UniProt: Q9GZQ8
Catalog #MBS841393
Price$335
Order / More InfoLC3B (Cleaved) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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