TXNIP (N-term), 1-30 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TXNIP (N-term), 1-30 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This TXNIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TXNIP. TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. |
| Immunogen | n/a |
| Other Names | [Thioredoxin-interacting protein; Thioredoxin-binding protein 2; Vitamin D3 up-regulated protein 1; TXNIP; VDUP1] |
| Gene, Accession # | [TXNIP], Gene ID: 10628, NCBI: NP_006463.3, UniProt: Q9H3M7 |
| Catalog # | MBS9202043 |
| Price | $165, $370 |
| Order / More Info | TXNIP (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zhuo de, X., et al. J. Biol. Chem. 285(41):31491-31501(2010) Kwon, H.J., et al. J. Immunol. 185(7):3980-3989(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Yu, F.X., et al. J. Biol. Chem. 285(33):25822-25830(2010) Cadenas, C., et al. Breast Cancer Res. 12 (3), R44 (2010) : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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