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Antigenic Specificity | Insulin R (Phospho Thr1375) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Insulin R (T1375) Polyclonal Antibody detects endogenous levels of Insulin R protein only when phosphorylated at T1375. INSR encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative spl |
Immunogen | Immunogen: Synthesized peptide derived from human Insulin R around the phosphorylation site of T1375 |
Other Names | [Rabbit Insulin R (phospho Thr1375); Insulin receptor; IR; CD antigen CD220] |
Gene, Accession # | [INSR], Gene ID: 3643, NCBI: NP_000199.2, UniProt: P06213 |
Catalog # | MBS9705546 |
Price | $130, $220, $325 |
Order / More Info | Insulin R (Phospho Thr1375) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |