Insulin R (Phospho Thr1375) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityInsulin R (Phospho Thr1375)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: Phospho-Insulin R (T1375) Polyclonal Antibody detects endogenous levels of Insulin R protein only when phosphorylated at T1375. INSR encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative spl
ImmunogenImmunogen: Synthesized peptide derived from human Insulin R around the phosphorylation site of T1375
Other Names[Rabbit Insulin R (phospho Thr1375); Insulin receptor; IR; CD antigen CD220]
Gene, Accession #[INSR], Gene ID: 3643, NCBI: NP_000199.2, UniProt: P06213
Catalog #MBS9705546
Price$130, $220, $325
Order / More InfoInsulin R (Phospho Thr1375) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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