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Antigenic Specificity | PERK |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 0.68-0.70 ug/ul in antibody stabilization buffer |
Applications | Dot Blot (DB), ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Eukaryotic translation initiation factor 2-alpha kinase 3 Antibody. Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 1000-1050 on human Eukaryotic translation initiation factor 2-alpha kinase 3 protein. Expression: Ubiquitous. A high level expression is seen in secretory tissues. |
Other Names | [DKFZp781H1925; E2AK3_HUMAN; EC 2.7.11.1; Eif2ak3; Eukaryotic translation initiation factor 2 alpha kinase 3; Heme regulated EIF2 alpha kinase; HRI; HsPEK; Pancreatic eIF2 alpha kinase; PEK; PRKR like endoplasmic reticulum kinase; WRS], [EIF2AK3; EIF2AK3; PEK; WRS; PERK; PEK; PERK; HsPEK] |
Gene, Accession # | [PERK], Gene ID: 9451, NCBI: NP_004827, UniProt: Q9NZJ5 |
Catalog # | MBS540843 |
Price | $390 |
Order / More Info | PERK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |