PERK Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPERK
Clonepolyclonal
Host SpeciesChicken
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentration0.68-0.70 ug/ul in antibody stabilization buffer
ApplicationsDot Blot (DB), ELISA (EIA), Western Blot (WB)
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DescriptionAffinity Purified Eukaryotic translation initiation factor 2-alpha kinase 3 Antibody. Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function.
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 1000-1050 on human Eukaryotic translation initiation factor 2-alpha kinase 3 protein. Expression: Ubiquitous. A high level expression is seen in secretory tissues.
Other Names[DKFZp781H1925; E2AK3_HUMAN; EC 2.7.11.1; Eif2ak3; Eukaryotic translation initiation factor 2 alpha kinase 3; Heme regulated EIF2 alpha kinase; HRI; HsPEK; Pancreatic eIF2 alpha kinase; PEK; PRKR like endoplasmic reticulum kinase; WRS], [EIF2AK3; EIF2AK3; PEK; WRS; PERK; PEK; PERK; HsPEK]
Gene, Accession #[PERK], Gene ID: 9451, NCBI: NP_004827, UniProt: Q9NZJ5
Catalog #MBS540843
Price$390
Order / More InfoPERK Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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