Edit |   |
Antigenic Specificity | Ran |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2b |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Mouse IgG monoclonal antibody for Ran detection. Tested with WB, ICC/IF, FCM in Human; Mouse; Rat.Background: RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the micr |
Immunogen | Immunogen: E Coli-derived human Ran recombinant protein (Position: A2-L216). Human Ran shares 100% amino acid (aa) sequence identity with both mouse and rat Ran. Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Relevant Detection Systems: Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (MBS176453) for ICC. |
Other Names | [GTP-binding nuclear protein Ran; RAN, member RAS oncogene family; GTP-binding nuclear protein Ran; Androgen receptor-associated protein 24; GTPase Ran; Ras-like protein TC4; Ras-related nuclear protein; RAN; ARA24; OK/SW-cl.81] |
Gene, Accession # | [Ran], Gene ID: 5901, NCBI: NP_006316.1, UniProt: P62826 |
Catalog # | MBS1752787 |
Price | $280 |
Order / More Info | Ran Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Avis JM, Clarke PR (October 1996). Ran, a GTPase involved in nuclear processes: its regulators and effectors. J. Cell. Sci. 109 (10): 2423-7. 2. Ciciarello M, Mangiacasale R, Lavia P (August 2007). Spatial control of mitosis by the GTPase Ran. Cell. Mol. Life Sci. 64 (15): 1891-914. 3. Moore MS, Blobel G (May 1994). A G protein involved in nucleocytoplasmic transport: the role of Ran. Trends Biochem. Sci. 19 (5): 211-6. |