PERK Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPERK
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: PERK Polyclonal Antibody detects endogenous levels of PERK protein. The protein encoded by EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3) phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in EIF2AK3 are associated with Wolcott-Rallison syndrome.
ImmunogenImmunogen: Synthesized peptide derived from human PERK around the non-phosphorylation site of T981
Other Names[Rabbit PERK; EIF2AK3; PEK; PERK; Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK]
Gene, Accession #[PERK], Gene ID: 9451, NCBI: NP_004827.4, UniProt: Q9NZJ5
Catalog #MBS9700767
Price$250, $250
Order / More InfoPERK Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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