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Antigenic Specificity | Tau |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, chicken, bovine |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in paired helical filaments (PHF), the major fibrous component of neurofibrillary lesions associated with Alzheimer's disease. Hyperphosphorylation of Tau is thomught to be the critical event leading to the assembly of PHF. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK3. This presents the possibility that miscues in GSK3 signaling contribute to the onset of Alzheimer's disease. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 395 of rat Tau |
Other Names | n/a |
Gene, Accession # | [Tau] |
Catalog # | MBS840818 |
Price | $150, $290 |
Order / More Info | Tau Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |