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Antigenic Specificity | WHSC2 |
Clone | [4E2] |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein compl |
Immunogen | Immunogen: Purified recombinant fragment of human WHSC2 (AA: 280-511) expressed in E. Coli. |
Other Names | [NELFA; NELF-A; P/OKcl.15] |
Gene, Accession # | [WHSC2], Gene ID: 7469, NCBI: Q9H3P2.3, UniProt: Q9H3P2 |
Catalog # | MBS8539282 |
Price | $280 |
Order / More Info | WHSC2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |