SOD (EC) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySOD (EC)
Clone[4GG11G6]
Host SpeciesMouse
Reactive Specieshuman, rat, mouse
IsotypeIgG1 kappa
Formatstreptavidin conjugate
Size0.1 mg
Concentration1mg/mL
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
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DescriptionBackground Info: Detects EC SOD at ~35kDa. Does not cross react with other SODs. Scientific Background: Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2 to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2, 5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are three types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganes
Immunogenn/a
Other Names[EC-SOD; MGC20077; EC 1.15.1.1; SOD3; EC SOD], [SOD3; SOD3; EC-SOD; EC-SOD]
Gene, Accession #Gene ID: 6649, NCBI: NP_003093.2, UniProt: P08294
Catalog #MBS800091
Price$430
Order / More InfoSOD (EC) Antibody from MYBIOSOURCE INC.
Product Specific References1. Adachi T., et al. (1992) Clin Chim Acta. 212: 89-102. 2. Barrister J.V., et al. (1987). Crit. Rev. Biochem. 22:111-180. 3. FurukawaY., and O'Halloran T. (2006) Antioxidants & Redo Signaling. 8(5): 6. 4. Gao B., et al. (2003) Am J Physiol Lung Cell Mol Physiol 284: L917-L925. 5. Hassan H.M. (1988) Free Radical Biol. Med. 5: 377-385. 6. Wispe J.R., et al. (1989) BBA. 994: 30-36. 7. Regan, E. et al. (2005) Arthritis & Rheumatism 52(11): 3479-3491 1. Tollefson, A.K. et al. (2010). Endogenous enzymes (NOX and ECSOD) regulate smoke-induced oxidative stress. Free Radical Biol and Med. 49 (12), 1937-1946. doi.org/10.1016/j.freeradbiomed.2010.09.022 2. Konior, A. et al. (2011). Seasonal superoxide overproduction and endothelial activation in guinea-pig heart; seasonal oxidative stress in rats and humans. J Mol Cel Cardiology. 50 (4), 686-694. doi:10.1016/j.yjmcc.2010.11.010
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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