NTRK1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-NTRK1 antibody, protein, ELISA kits.
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| Antigenic Specificity | NTRK1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The family of Trk receptor tyrosine kinases consists of TrkA, TrkB, and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3 (1). Neurotrophin signaling through these receptors regulates a number of physiological processes, such as cell survival, proliferation, neural development, and axon and dendrite growth and patterning (1). In the adult nervous system, the Trk receptors regulate synaptic strength and plasticity. TrkA regulates proliferation and is important for development and maturation of the nervous system (2). Phosphorylation at Tyr490 is required for Shc association and activation of the Ras-MAP kinase cascade (3, 4). |
| Immunogen | Immunogen: A synthetic peptide of human NTRK1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA] |
| Gene, Accession # | [NTRK1], Gene ID: 4914, NCBI: NP_001007793.1, UniProt: P04629 |
| Catalog # | MBS8505794 |
| Price | $310 |
| Order / More Info | NTRK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Huang, E.J. and Reichardt, L.F. (2003) Annu Rev Biochem 72, 609-42. 2. Segal, R.A. and Greenberg, M.E. (1996) Annu Rev Neurosci 19, 463-89. 3. Stephens, R.M. et al. (1994) Neuron 12, 691-705. 4. Marsh, H.N. et al. (2003) J Cell Biol 163, 999-1010. 5. Obermeier, A. et al. (1993) EMBO J 12, 933-41. 6. Obermeier, A. et al. (1994) EMBO J 13, 1585-90. 7. Arevalo, J.C. et al. (2001) Oncogene 20, 1229-34. 8. Reuther, G.W. et al. (2000) Mol Cell Biol 20, 8655-66. 9. Greco, A. et al. (1997) Genes Chromosomes Cancer 19, 112-23. 10. Pierotti, M.A. and Greco, A. (2006) Cancer Lett 232, 90-8. 11. Lagadec, C. et al. (2009) Oncogene 28, 1960-70. 12. Greco, A. et al. (2010) Mol Cell Endocrinol 321, 44-9. 13. Odegaard, E. et al. (2007) Hum Pathol 38, 140-6. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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