RAB7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRAB7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: RAB7 antibody detects endogenous levels of total RAB7. Function: Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth-factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism. Also involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes, pathogen-induced p
ImmunogenImmunogen: A synthesized peptide derived from human RAB7 Subcellular Location: Late endosome. Lysosome. Cytoplasmic Vesicle > Phagosome. Melanosome. Cytoplasmic Vesicle > Phagosome Membrane. Co-localizes with OSBPL1A at the late endosome. Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts. Recruited to phagosomes containing S.aureus or Mycobacterium. Tissue Specificity: Widely expressed; high expression found in skeletal muscle.
Other Names[CMT2B; PRO2706; PSN; RAB7, member RAS oncogene family; RAB7A; RAB7A, member RAS oncogene family; RAB7A_HUMAN; Ras associated protein RAB7; Ras related protein Rab7; Ras related protein Rab7a; Ras-related protein Rab-7a]
Gene, Accession #[RAB7], Gene ID: 7879, NCBI: NP_004628.4, UniProt: P51149
Catalog #MBS9608155
Price$240, $280
Order / More InfoRAB7 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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