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Antigenic Specificity | Phospho-RPA2 (T21) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-RPA2 (T21) Antibody detects endogenous levels of Phospho-RPA2 (T21). As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-RPA2 (T21) |
Other Names | [REPA2; RF-A; RP-A; RPA2; RPA32; replication factor-A protein 2; replication protein A 32 kDa subunit; replication protein A2] |
Gene, Accession # | [RPA2], Gene ID: 6118, NCBI: NP_001273005.1, UniProt: P15927 |
Catalog # | MBS4750391 |
Price | $335 |
Order / More Info | Phospho-RPA2 (T21) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |