Stat3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityStat3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionBackground: Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-alpha and form a heterodimer which is part of the ISGF3 transcription factor complex. Althomugh early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3beta appears to be activated by both while Stat3alpha is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 is activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 73 of rat Stat3
Other Names[Signal transducer and activator of transcription 3; stat -3; STAT3; STAT -3; STAT 3; APRF; FLJ20882; MGC16063], [Stat3; Stat3; Aprf; AW109958; 1110034C02Rik; Aprf]
Gene, Accession #[Stat3], Gene ID: 20848, NCBI: AAA19452.1
Catalog #MBS841322
Price$150, $290
Order / More InfoStat3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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