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Antigenic Specificity | TLR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 200 ug/ml |
Applications | Flow Cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TLR4 is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type 1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine rich repeats and the intracellular domain is similar to that of IL 1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL 1 receptor for signal transduction that leads to activation of NF kB. |
Immunogen | Immunogen: TLR4 antibody was raised in Rabbit using recombinant human TLR4 as the immunogen. |
Other Names | [Rabbit TLR4; TLR4; TLR4; TLR-4; Toll like receptor 4; TLR4; TLR 4; TLR-4; TLR 4; TLR-4] |
Gene, Accession # | [TLR4], NCBI: ACX37356.1 |
Catalog # | MBS5309080 |
Price | $705 |
Order / More Info | TLR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |