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Antigenic Specificity | Apolipoprotein CIII |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Apolipoprotein C-III(APOC3) detection. Background: Apolipoprotein C-III, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene. Apo-CIII is a component of very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. |
Immunogen | Immunogen: E. coli-derived human Apolipoprotein CIII recombinant protein (Position: S21-A99). Human Apolipoprotein CIII shares 55.3% and 54.3% amino acid (aa) sequence identity with mouse and rat Apolipoprotein CIII, respectively. |
Other Names | [APOC3; APO C3; APOC 3; APOC3; Apo CIII; Apo-CIII; ApoC III; ApoC-III; ApoCIII; Apolipoprotein C III; Apolipoprotein C-III; Apolipoprotein C3; ApolipoproteinCIII; P02656], [APOC3; APOC3; HALP2; APOCIII; Apo-CIII; ApoC-III] |
Gene, Accession # | [APOC3], Gene ID: 345, NCBI: NP_000031.1, UniProt: P02656 |
Catalog # | MBS178799 |
Price | $280 |
Order / More Info | Apolipoprotein CIII Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Nicolardi S, van der Burgt YE, Dragan I, Hensbergen PJ, Deelder AM (May 2013). Identification of new apolipoprotein-CIII glycoforms with ultrahigh resolution MALDI-FTICR mass spectrometry of human sera.Journal of Proteome Research 12 (5): 2260-8.2. Vaith P, Assmann G, Uhlenbruck G (Jun 1978). Characterization of the oligosaccharide side chain of apolipoprotein C-III from human plasma very low density lipoproteins. Biochimica et Biophysica Acta 541(2): 234-40. |