Chk1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityChk1
Clone[2G1D5]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
FormatProtein G purified
Size0.05 mg
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionMouse anti Chk1 antibody, clone 2G1D5 recognizes Chk1 also known as cell cycle checkpoint kinase homologue 1, CHK1 or checkpoint kinase-1. Chk1, like the other checkpoint kinase Chk2, is a serine/threonine protein kinase that plays a crucial role in cell cycle control. Chk1 becomes phosphorylated and consequently activated in response to DNA damage by the ATR kinase. Upon this activation Chk1 phosphorylates a variety of proteins including p53 and Cdc25, which triggers cell cycle arrest, DNA repair and apoptosis (Bartek and Lukas, 2003). Chk1 plays a critical role in preventing aberrant cells from progressing through the cell cycle. Based on this, it is not surprising that Chk1 is of interest in the field of cancer research and as a therapeu
ImmunogenImmunogen: Recombinant human Chk1
Other Names[Chk1], [CHEK1; CHEK1; CHK1; CHK1]
Gene, Accession #[CHEK1], Gene ID: 1111, NCBI: O14757.2, UniProt: O14757
Catalog #MBS225380
Price$405
Order / More InfoChk1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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